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Cardiomyocytes are formidable protein synthesis factories, producing around 14,000 proteins, rendering them particularly vulnerable to accumulating toxic levels of misfolded proteins in times of stress, such as in AF due to the rapid activation rates and enhanced mechanical and metabolic stress [8]

Furthermore, OHP causes damage to both neuronal and nonneuronal mitochondria, leading to oxidative stress burden mediated by the redox-sensitive TRPA1 channels, which correlate with OHP-induced cold and mechanical hypersensitivity [71, 115,116,117]

Evaluation of the antioxidant potential of natural food/plant extracts as compared with synthetic antioxidants and vitamin E in raw and cooked pork patties

eBioMedicine (2022) 76:103861

Results of our measurement have shown a lower cortisol concentration in samples of saliva in comparison to concentrations of cortisol in samples of serum, as well as in samples that were taken before noon and afternoon hours