not responding to b12 injections Working? Your Cofactors Might Be the Problem : r/B12_Deficiency B12 Shots at Home: How,

Treatment duration varies: 8-12 weeks for neuropathy, 4 weeks for energy restoration, or indefinitely for chronic conditions like pernicious anemia

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B12 does not stack: once your blood level is in the normal range, extra B12 is simply passed out in your urine rather than converted into more energy

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So, if you are eating a varied diet and do not have a laboratory-documented vitamin B12 deficiency, you do not need additional supplementation. However, she explains people who subscribe to strict vegan or vegetarian diets are much more likely to be at risk of vitamin B12 deficiency, and they should take supplemental B12, especially when pregnant or trying to become pregnant