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Subsequently, caspase-1 is activated, which in turn cleaves Gasdermin D (GSDMD), leading to cell membrane perforation and release of interleukin-18 (IL-18) and IL-1, ultimately resulting in cell swelling and pyroptosis (Liu et al., 2024)

Stroke has been identified to be the third major contributor to disability globally, accounting for 143.23 million disability-adjusted life years (DALYs) in 2019, which is 32% more than the year 1990 [1]

Chronic obstructive pulmonary disease: an emerging comorbidity in HIV-infected patients in the HAART era

Tyrosinemia is treated with medicine and a low-tyrosine diet

Plasma steroid concentrations in male rhesus monkeys following treatment with the P450c17 (CYP17) inhibitors VT-464 and abiraterone acetate: a comparison to human 17,20-Lyase (lyase) and combined lyase/17-hydroxylase (hydroxylase) deficiencies [abstract]