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Full article: Targeting Cellular Senescence for Healthy Aging: Advances in Senolytics and Senomorphics A biological miracle is happening in anti aging where the body takes out the trash. The peptide reduced frailty markers by 50% in aged mice, inducing apoptosis (death) only in damaged cells. It FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology Targeting Cellular Senescence in Aging and Age Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic Therapies Computational design of peptide targeting FOXO4. a, Domains of FOXO4 Download Scientific Diagram Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv

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