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However, low adherence as well as limited LDL-C efficacy in HoFH patients with markedly reduced LDL receptor (LDLR) activity, 6 results in a low LDL-C goal achievement in most patients

Many of these pharmacologic agents under investigation are hypothesized to target the direct and indirect mechanisms of neurotoxicity but require additional efficacy and safety data before being recommended for use in clinical practice

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As research is finding: Several lines of evidence suggest that adult neurogenesis, the production of new neurons in adulthood, may play a role in psychiatric disorders, including depression, anxiety, and schizophrenia

Furthermore, we analyzed the orientation of drug molecules within the phospholipid membrane to better understand the details of their interaction

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