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TB500 peptide and injectable GHK-CU formulations are prohibited for compounding under current FDA regulations due to identified safety risks and insufficient human safety data

The latter fact is important as it confirms the potential of IGF-1 DES to improve anabolism even in the setting of poor calorie intake, a function that would make the peptide useful in chronic disease and in individuals who are unable to consume a great deal of calories for a variety of reasons

This maximizes BPC-157's local effects while ensuring TB-500's systemic benefits reach all tissues

However, they are also effective independently

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