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10.1016/j.brainres.2015.09.034 177 PatelS

doi: 10.3389/fimmu.2024.1464923 Received 15 July 2024 Accepted 11 September 2024 Published 04 October 2024 Volume 15 - 2024 Edited by Mahavir Singh, LIONEX GmbH, Germany Reviewed by Gareth Jones, Animal and Plant Health Agency, United Kingdom Lucia Mori, University of Basel, Switzerland Updates Copyright 2024 Iacobino, Teloni, Mancone, Facchiano, Di Giamberardino, Senatore, Di Virgilio, Lanni, Giannoni, Nisini and Mariotti

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Side Effect 5: Systemic Effects Systemic reactions may include fatigue, anxiety, and numbness in extremities

Human induced pluripotent stem cell culture Human induced pluripotent stem cells (hiPSCs) lines, IMR90 (IMR90-4/WISCi004-B, RRID:CVCL_C437, WiCell), M001 (SCTi002-A, RRID:CVCL_9S50, STEMCELL Technologies Inc.), and Gibco (TMOi001-A, RRID:CVCL_RM92, Gibco Episomal hiPSC Line, Gibco) were routinely cultured on 5 g/mL human laminin 521 (Biolamina)-coated culture-treated six-well plates (CoStar), maintained in mTeSR Plus (STEMCELL Technologies) supplemented with 1% (v/v) Pen-Strep